CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18871
Family Name 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor ligand 7-[[4-(4-fluorobenzoyl)piperidin-1-yl]methyl]-2-(methylamino)-7,8-dihydro-6H-quinazolin-5-one family
No. of Seeds 1 No. of Other Members 11
Family Centroid CFAMM00449500 Functional Category Bioactive with Natural Product
Superfamily Mast/stem cell growth factor receptor Kit and Abelson tyrosine-protein kinase 2 Inhibitor Imatinib Superfamily
Class Class 144

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Adenosine receptor A1 Ligand N-(4,6-diphenylpyrimidin-2-yl)ben... 4 8
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-amin... 10 48
Cell division cycle 7-related protein kinase inhibitor pyrrolo... 4 10
Heat shock protein HSP 90-beta inhibitor 1-(2-amino-4-methylqu... 1 2
Substance-P receptor ligand 2-[3,5-bis(trifluoromethyl)phenyl]... 3 1
Cathepsin K and Cathepsin S inhibitor 2-Cyano-pyrimidine, 17d ... 5 9
G-protein coupled bile acid receptor 1 ligand 2-(ethylamino)-6... 5 4
Macrophage colony-stimulating factor 1 receptor and Mast/stem ... 27 4
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 2
Mast/stem cell growth factor receptor Kit and Tyrosine-protein... 4 1
Poly [ADP-ribose] polymerase 1 inhibitor Piperazine analogue, ... 4 0
Transcription factor AP-1 and Nuclear factor NF-kappa-B p105 s... 2 4
Amine oxidase [flavin-containing] B and Metabotropic glutamate... 2 0
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 inhibi... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449500 CHEMBL583772 Bioactive 7-[[4-(4-fluorobenzoyl)piperidin-1-yl]methyl]-2-(methylamino)-7,8-dihydro-6H-quinazolin-5-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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