CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18875
Family Name Rho-associated protein kinase 1 inhibitor AGN-PC-07COKD family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00449540 Functional Category Bioactive
Superfamily Substance-P receptor and Dipeptidyl peptidase 4 Binder Superfamily 2
Class Class 1031

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Transient receptor potential cation channel subfamily V member... 15 457
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Amg 423 family 7 47
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... 4 9
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 2 6
Histamine H4 receptor Ligand A-943931 Family 14 11
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Transient receptor potential cation channel subfamily V member... 4 0
Glutamate receptor ionotropic, NMDA 2B ligand SureCN5351665 fa... 5 4
Nociceptin receptor and Mu-type opioid receptor ligand SureCN5... 1 0
Metabotropic glutamate receptor 1 ligand AGN-PC-00FV3S family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449540 CHEMBL584291 Bioactive AGN-PC-07COKD

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27264 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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