CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18896
Family Name Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R96X family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00449616 Functional Category Bioactive
Superfamily Coagulation factor X and C-X-C chemokine receptor type 3 Binder Superfamily
Class Class 2337

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 16 295
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Kappa-type opioid receptor Ligand Brl 52974 Family 2 27
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Platelet-activating factor receptor ligand SureCN9523843 family 4 4
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 9
Vasopressin V1b receptor ligand 2-[3-(3-chlorophenyl)-1-oxo-7-... 2 12
Cell division cycle 7-related protein kinase and Cyclin-depend... 2 9
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 1 0
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Coagulation factor X inhibitor SureCN8289965 family 4 5
Vascular endothelial growth factor receptor 2 ligand (3Z)-3-[5... 4 11
C-C chemokine receptor type 4 ligand [4-[4-[(2,4-dichloropheny... 4 4
P2X purinoceptor 7 inhibitor SureCN109432 family 10 28
P2X purinoceptor 7 inhibitor SureCN9931311 family 2 0
P2X purinoceptor 7 inhibitor SureCN113576 family 2 1
Substance-K receptor ligand SureCN9035669 family 10 5
Tripeptidyl-peptidase 2 inhibitor (2S)-2-amino-1-[(2S)-5-chlor... 1 0
Nitric oxide synthase, inducible inhibitor N-[(4-chlorophenyl)... 2 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Mitogen-activated protein kinase 14 inhibitor SureCN14185127 f... 2 0
Mitogen-activated protein kinase 1 and Aurora kinase A inhibit... 16 3
Poly [ADP-ribose] polymerase 1 inhibitor SureCN3553433 family 22 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R9GP family 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449617 CHEMBL591515 Bioactive AGN-PC-07R96Z
CFAMM00449616 CHEMBL604040 Bioactive AGN-PC-07R96X
CFAMM00449614 CHEMBL596713 Bioactive AGN-PC-07R9L5
CFAMM00449620 CHEMBL589257 Bioactive AGN-PC-07R96Y
CFAMM00449613 CHEMBL603135 Bioactive AGN-PC-07R99K
CFAMM00449619 CHEMBL603457 Bioactive SureCN3561316
CFAMM00449618 CHEMBL590805 Bioactive 6,7-dichloro-4-[[4-fluoro-3-(4-isoquinolin-3-ylpiperazine-1-carbonyl)phenyl]methyl]-2H-pyrrolo[1,2-a]pyrazin-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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