CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM189
Family Name Beta-3 adrenergic receptor and Beta-2 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-(3-octyl-2-oxoimidazolidin-1-yl)benzenesulfonamide family
No. of Seeds 19 No. of Other Members 53
Family Centroid CFAMM00308598 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Beta-2 adrenergic receptor Binder Superfamily 2
Class Class 2668

Cousin Family NamesSeedsMembers
Solute carrier family 12 member 1 Inhibitor Torasemide Family 13 75
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 26 47
Pol polyprotein inhibitor Lysine Sulfonamide 6h family 1 1
Pol polyprotein inhibitor AC1LAHQ9 family 8 15
Pol polyprotein inhibitor AC1LAHRX family 4 0
Nicotinamide phosphoribosyltransferase inhibitor 1-[4-(8-oxa-3... 5 4
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 4
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 5 1
Beta-3 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-p... 4 10
Nicotinamide phosphoribosyltransferase inhibitor pyridin-3-ylm... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308599 CHEMBL349505 Bioactive 4-[3-[(3,4-difluorophenyl)methyl]-2-oxoimidazol-1-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00308638 CHEMBL22318 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-(4-octyl-5-oxotetrazol-1-yl)benzenesulfonamide
CFAMM00308605 CHEMBL350590 Bioactive 4-[3-(2-cyclohexylethyl)-2-oxoimidazolidin-1-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00308664 CHEMBL351596 Bioactive 4-[3-(2,2-dimethylhexyl)-2-oxoimidazolidin-1-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00308644 CHEMBL309628 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-(4-octyl-5-oxo-1,2,4-triazolidin-1-yl)benzenesulfonamide
CFAMM00308598 CHEMBL84190 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-(3-octyl-2-oxoimidazolidin-1-yl)benzenesulfonamide
CFAMM00308650 CHEMBL83753 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-(3-octyl-2-oxoimidazol-1-yl)benzenesulfonamide
CFAMM00308643 CHEMBL349651 Bioactive 4-[3-(3-cyclopentylpropyl)-2-oxoimidazol-1-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00308649 CHEMBL83698 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-(3-octyl-2,4-dioxoimidazolidin-1-yl)benzenesulfonamide
CFAMM00308662 CHEMBL79806 Bioactive 4-(4-hexyl-5-oxo-1,2,4-triazol-1-yl)-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00308616 CHEMBL104193 Bioactive 1-[4-[[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]sulfamoyl]phenyl]-3-(2-phenylethyl)urea
CFAMM00308642 CHEMBL57486 Bioactive SureCN8790919
CFAMM00308667 CHEMBL323113 Bioactive 1-[4-[[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]sulfamoyl]phenyl]-3-octylurea
CFAMM00308627 CHEMBL350931 Bioactive 4-[3-[(3,4-difluorophenyl)methyl]-2-oxoimidazolidin-1-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00308620 CHEMBL166188 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-[2-oxo-3-(3-phenylpropyl)imidazolidin-1-yl]benzenesulfonamide
CFAMM00308646 CHEMBL22317 Bioactive L-766892
CFAMM00308613 CHEMBL163579 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-(4-octyl-5-oxo-1,2,4-triazol-1-yl)benzenesulfonamide
CFAMM00308652 CHEMBL162043 Bioactive 4-[3-[3-(4-chlorophenyl)propyl]-2-oxoimidazolidin-1-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00308665 CHEMBL165177 Bioactive 4-[3-(3-cyclohexylpropyl)-2-oxoimidazolidin-1-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24336 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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