CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18902
Family Name Poly [ADP-ribose] polymerase 1 inhibitor SureCN3553433 family
No. of Seeds 22 No. of Other Members 0
Family Centroid CFAMM00449681 Functional Category Bioactive
Superfamily Poly [ADP-ribose] polymerase 1 and Prothrombin Binder Superfamily
Class Class 1555

Cousin Family NamesSeedsMembers
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Reverse transcriptase Inhibitor IDX899 Family 2 118
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Prothrombin inhibitor SureCN7371121 family 13 3
Huntingtin and Glycogen synthase kinase-3 beta inhibitor SB 21... 2 4
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 1 10
Cannabinoid receptor 1 ligand AGN-PC-04YSUM family 7 6
Vasopressin V1b receptor ligand 2-[3-(3-chlorophenyl)-1-oxo-7-... 2 12
Translocator protein inhibitor (2E)-N-(4-chlorophenyl)-N-methy... 2 13
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 21
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 1 2
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Cannabinoid receptor 1 ligand 5-cyano-1-[(3,5-dichlorophenyl)m... 2 0
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6R... 2 2
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 12
D(3) dopamine receptor and Alpha-1D adrenergic receptor ligand... 1 0
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 2 9
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Di... 2 3
Beta-secretase 1 and Potassium voltage-gated channel subfamily... 2 11
Beta-secretase 2 and Beta-secretase 1 inhibitor N-[3-[(1S,7S)-... 7 4
Beta-secretase 1 and Beta-secretase 2 inhibitor N-[3-[(4S)-2-a... 6 4
Seprase and Prolyl endopeptidase inhibitor 7-chloro-N-[2-[(2S)... 3 3
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 17 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 5 8
Coagulation factor X and Prothrombin inhibitor N,1-bis[(3-carb... 1 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Translocator protein inhibitor 2-(7-Chloro-5-methyl-4-oxo-3-ph... 1 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R96X family 7 1
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R9GP family 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449672 CHEMBL598544 Bioactive SureCN3557415
CFAMM00449669 CHEMBL589833 Bioactive AGN-PC-07NC1C
CFAMM00449678 CHEMBL603407 Bioactive AGN-PC-07R9L6
CFAMM00449668 CHEMBL601260 Bioactive AGN-PC-07R9AY
CFAMM00449684 CHEMBL590579 Bioactive AGN-PC-07R9CD
CFAMM00449677 CHEMBL590791 Bioactive AGN-PC-07NC0Q
CFAMM00449667 CHEMBL597925 Bioactive SureCN3552056
CFAMM00449683 CHEMBL592543 Bioactive AGN-PC-07R9HY
CFAMM00449676 CHEMBL603873 Bioactive SureCN3558487
CFAMM00449666 CHEMBL590327 Bioactive SureCN3916868
CFAMM00449682 CHEMBL589575 Bioactive SureCN3561564
CFAMM00449675 CHEMBL597324 Bioactive SureCN3552084
CFAMM00449665 CHEMBL602535 Bioactive AGN-PC-07R94N
CFAMM00449681 CHEMBL597117 Bioactive SureCN3553433
CFAMM00449674 CHEMBL606029 Bioactive AGN-PC-07NC12
CFAMM00449671 CHEMBL605284 Bioactive AGN-PC-07R9HX
CFAMM00449680 CHEMBL597116 Bioactive SureCN3553657
CFAMM00449664 CHEMBL590088 Bioactive AGN-PC-07R9CC
CFAMM00449673 CHEMBL598543 Bioactive SureCN3559536
CFAMM00449670 CHEMBL589834 Bioactive AGN-PC-07R9AX
CFAMM00449679 CHEMBL590880 Bioactive SureCN3560547
CFAMM00449663 CHEMBL604547 Bioactive AGN-PC-07R99L

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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