CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1891
Family Name Vasopressin V1b receptor ligand 2-[3-(3-chlorophenyl)-7-[3-(3-fluoropiperidin-1-yl)propoxy]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide family
No. of Seeds 8 No. of Other Members 17
Family Centroid CFAMM00328609 Functional Category Bioactive
Superfamily B1 bradykinin receptor and Cytochrome P450 3A4 Binder Superfamily
Class Class 1652

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 3 0
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Sonic hedgehog protein inhibitor 6-ethyl-3-(2-fluoroethoxy)-N-... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00328609 CHEMBL1222546 Bioactive 2-[3-(3-chlorophenyl)-7-[3-(3-fluoropiperidin-1-yl)propoxy]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
CFAMM00328608 CHEMBL1223261 Bioactive 2-[3-(3-chlorophenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
CFAMM00328601 CHEMBL1223336 Bioactive 2-[3-(3-chloro-4-fluorophenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
CFAMM00328620 CHEMBL1223402 Bioactive 2-[3-[4-fluoro-3-(trifluoromethyl)phenyl]-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
CFAMM00328613 CHEMBL1222548 Bioactive 2-[3-(3-chlorophenyl)-1-oxo-7-[3-[4-(trifluoromethyl)piperidin-1-yl]propoxy]pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
CFAMM00328618 CHEMBL1222547 Bioactive 2-[3-(3-chlorophenyl)-1-oxo-7-[3-[3-(trifluoromethyl)pyrrolidin-1-yl]propoxy]pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
CFAMM00328617 CHEMBL1223545 Bioactive N-tert-butyl-2-[3-(3-chlorophenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]acetamide
CFAMM00328610 CHEMBL1222688 Bioactive 2-[3-(3-chlorophenyl)-7-(1-cyclopentylpiperidin-4-yl)oxy-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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