CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1892
Family Name Histamine H1 receptor and Alpha-1B adrenergic receptor ligand 4-piperazin-1-yl-10H-imidazo[1,2-b][2]benzazepine family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00328629 Functional Category Bioactive
Superfamily Histamine H1 receptor and Alpha-1B adrenergic receptor Binder Superfamily 2
Class Class 1237

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 Inhibitor Clotrimazole Family 16 145
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
14-alpha sterol demethylase Inhibitor Butoconazole Family 2 53
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Telomerase protein component 1 Inhibitor GRN163L Family 5 29
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Aromatase and Thromboxane-A synthase Inhibitor 6-(1h-imidazol-... 3 8
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-aminobenzyl... 3 6
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 45
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 6 6
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 2 1
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 2 8
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 4
Prelamin-A/C inhibitor CHEMBL1611943 family 1 9
Delta-type opioid receptor and Kappa-type opioid receptor liga... 10 4
5-hydroxytryptamine receptor 2B ligand SureCN1299437 family 6 7
5-hydroxytryptamine receptor 2A and Histamine H1 receptor liga... 6 2
Histamine H1 receptor ligand 3-[4-(10H-imidazo[1,2-b][2]benzaz... 2 0
Alpha-1A adrenergic receptor ligand 2-[4-[(3,3-difluoroazetidi... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00328629 CHEMBL1222552 Bioactive 4-piperazin-1-yl-10H-imidazo[1,2-b][2]benzazepine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543