CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18924
Family Name 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2B ligand AGN-PC-00CQ29 family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00262676 Functional Category Bioactive with Natural Product
Superfamily Vasopressin V2 receptor and Prelamin-A/C Binder Superfamily
Class Class 1375

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Alpha adrenergic receptor Ligand Droperidol Family 20 244
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
5-hydroxytryptamine 2 receptor Ligand Ketanserin Family 10 253
Motilin receptor Ligand GSK962040 Family 30 457
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
K-604 family 4 71
Amonafide family 3 35
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 19 186
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Integrin beta-3 Inhibitor SB-208651 Family 9 28
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Arachidonate 5-lipoxygenase Inhibitor Isaindigotone Family 1 0
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor Benz... 3 12
cAMP-specific 3',5'-cyclic phosphodiesterase 4B Inhibitor 3-(2... 2 2
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
D(2) dopamine receptor Ligand PD-168077 Family 6 5
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEDE family 7 17
C-C chemokine receptor type 3 ligand SureCN6703027 family 2 1
Vasopressin V2 receptor ligand [2-chloro-4-(prop-2-enylamino)p... 3 14
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 53
DNA-(apurinic or apyrimidinic site) lyase and Niemann-Pick C1 ... 1 1
Hypoxia-inducible factor 1-alpha and Ubiquitin carboxyl-termin... 1 1
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 8 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 6
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6S... 2 4
C-C chemokine receptor type 3 and Sodium-dependent serotonin t... 12 2
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5 19
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
P2X purinoceptor 7 inhibitor 2-[3-fluoro-4-(trifluoromethyl)ph... 3 0
Phospholipase D1 and Phospholipase D2 inhibitor 4-bromo-N-[(2S... 1 2
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4... 5 1
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(3... 2 4
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
Beta-secretase 1 and Beta-secretase 2 inhibitor AC1N6ZLA family 1 0
Vascular endothelial growth factor receptor 2 ligand isoindoli... 1 0
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
Muscarinic acetylcholine receptor M2 ligand AGN-PC-073RRB family 2 1
Mitogen-activated protein kinase 14 and Serine/threonine-prote... 1 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
Aldose reductase inhibitor (4R)-6-fluoro-3-methylspiro[1H-quin... 4 16
Glutamate receptor ionotropic, kainate 1 and Glutamate recepto... 1 12
Putative NP ZINC40310029 Family 8 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449771 CHEMBL590580 Bioactive SureCN4042696

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23731 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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