CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18929
Family Name Peroxisome proliferator-activated receptor gamma ligand AGN-PC-07RBFI family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00449806 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Proto-oncogene tyrosine-protein kinase Src Binder Superfamily
Class Class 1994

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Bacterial outer membrane Inhibitor Daptomycin Family 6 50
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
BIBT986 family 7 96
Setipiprant family 5 118
Eluxadoline family 4 85
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Microsomal triglyceride transfer protein large subunit Inhibit... 5 9
Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-d... 1 8
Cytosolic phospholipase A2 Inhibitor WAY-196025 Family 4 13
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family 3 8
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 27
Endothelin B receptor Ligand IRL-2500 Family 34 87
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 1 1
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16f ... 3 18
Vascular endothelial growth factor receptor 2 ligand indolyl q... 4 3
NS5B protein inhibitor AC1NQMYG family 6 12
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4R,... 3 7
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 36
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QM95 family 1 1
Prostaglandin E2 receptor EP4 subtype ligand SureCN3567929 family 10 3
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor AG... 1 0
Prostaglandin D2 receptor 2 ligand SureCN2189431 family 7 1
NS5B protein inhibitor AGN-PC-00A17Z family 1 23
NS5B protein inhibitor AC1O5AET family 3 1
NS5B protein inhibitor AC1NQMYP family 5 0
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 3 5
Prostaglandin D2 receptor 2 ligand 2-[1-(4-benzamidobenzoyl)is... 4 9
Cannabinoid receptor 1 ligand N-[2-(cyclopropylamino)-2-oxoeth... 5 5
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 7 15
5-hydroxytryptamine receptor 4 ligand 4-[2-[4-[[(1-propan-2-yl... 1 1
Prostaglandin D2 receptor 2 ligand 2-[(3R)-3-(3,3-diphenylprop... 1 0
Beta-2 adrenergic receptor ligand SureCN5346426 family 8 0
Beta-2 adrenergic receptor ligand SureCN4598646 family 7 7
High affinity nerve growth factor receptor ligand CHEMBL254555... 2 2
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Phospholipase A2, membrane associated inhibitor AGN-PC-075RBK ... 1 2
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 1 1
Gonadotropin-releasing hormone receptor ligand 4-[2-[[(2S)-2-[... 1 0
Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)met... 4 11
Glutamate receptor 4 and Glutamate receptor 2 ligand SureCN437... 4 12
Thrombopoietin receptor ligand AGN-PC-077M9L family 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449806 CHEMBL606422 Bioactive AGN-PC-07RBFI
CFAMM00449805 CHEMBL601222 Bioactive AGN-PC-07RBGD
CFAMM00449803 CHEMBL602468 Bioactive SureCN14120347
CFAMM00449808 CHEMBL590983 Bioactive AGN-PC-07RBGE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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