CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18946
Family Name Sodium-dependent noradrenaline transporter and Sodium-dependent serotonin transporter inhibitor SureCN4091725 family
No. of Seeds 12 No. of Other Members 16
Family Centroid CFAMM00449937 Functional Category Bioactive
Superfamily Sodium-dependent noradrenaline transporter and Mineralocorticoid receptor Binder Superfamily
Class Class 933

Cousin Family NamesSeedsMembers
Nociceptin receptor Ligand J-113397 Family 3 14
Protein kinase C eta type and Protein kinase C delta type Inhi... 9 12
Sphingosine kinase 2 Inhibitor (r)-2-amino-3-(4-octylphenylami... 1 16
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 5 29
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 4
Pol polyprotein inhibitor AC1LAMTL family 11 15
Vesicular acetylcholine transporter inhibitor N-ethyl-2-fluora... 2 7
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 11 9
Beta-secretase 1 and Cathepsin D inhibitor N-[4-[[(3S,4S,5R)-5... 1 12
Pol polyprotein inhibitor DMP-450 family 9 4
D(1A) dopamine receptor and D(3) dopamine receptor ligand 4-[(... 2 3
Neuropeptide Y receptor type 5 ligand 3-(4-benzylphenyl)-1-[(1... 2 4
Sodium-dependent dopamine transporter and Sigma non-opioid int... 3 10
Sodium-dependent noradrenaline transporter inhibitor SureCN408... 5 12
Vesicular acetylcholine transporter inhibitor (3R,4R)-1-[(4-fl... 2 0
Vesicular acetylcholine transporter inhibitor AGN-PC-00Q2L5 fa... 1 1
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN13328411 ... 4 2
D(1A) dopamine receptor and D(3) dopamine receptor ligand Sure... 1 0
2-(4-aminophenyl)-2-[[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-m... 2 1
2,6-dimethyl-1,2,3,4-tetrahydroquinolin-4-ol NP (2r,4s)-6-brom... 3 1


External ID

Functional Category

Molecule Name

CFAMM00449937 CHEMBL601880 Bioactive SureCN4091725
CFAMM00449928 CHEMBL598614 Bioactive SureCN4086802
CFAMM00449933 CHEMBL598168 Bioactive SureCN4081120
CFAMM00449926 CHEMBL597968 Bioactive SureCN4077110
CFAMM00449932 CHEMBL600220 Bioactive SureCN4077170
CFAMM00449931 CHEMBL600424 Bioactive SureCN4085205
CFAMM00449944 CHEMBL591928 Bioactive SureCN4079983

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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