CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18949
Family Name Tyrosine-protein kinase JAK2 inhibitor AGN-PC-04WVYY family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00449954 Functional Category Bioactive
Superfamily Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 Inhibitor Atropisomer 1 Superfamily
Class Class 931

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Tyrosine kinase Inhibitor PKI166 Family 17 198
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 13 15
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Histamine H4 receptor ligand AGN-PC-07ZG9H family 4 4
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 12 8
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Hepatocyte growth factor receptor ligand 4-[(6-phenyl-[1,2,4]t... 3 6
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 1 6
Insulin-like growth factor 1 receptor ligand 4-(2,3-dihydroind... 1 0
Estrogen receptor beta and Estrogen receptor ligand SureCN6442... 1 2
Vascular endothelial growth factor receptor 2 and Vascular end... 4 2
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-3-N-(7... 2 2
Type-1 angiotensin II receptor ligand SureCN7941428 family 2 2
Vascular endothelial growth factor receptor 2 ligand pyrimidin... 2 2
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-04WWHE family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449954 CHEMBL592033 Bioactive AGN-PC-04WVYY

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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