CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18955
Family Name Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta ligand SureCN4012454 family
No. of Seeds 14 No. of Other Members 2
Family Centroid CFAMM00449983 Functional Category Bioactive
Superfamily Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta Ligand WAY-254011 Superfamily
Class Class 3035

Cousin Family NamesSeedsMembers
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor GSK2... 15 18
Apricoxib family 8 77
Indeglitazar family 3 39
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 5
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 5
5-hydroxytryptamine receptor 6 ligand SureCN5502542 family 4 2
5-hydroxytryptamine receptor 6 ligand 1-[9-(benzenesulfonyl)-6... 11 2
Somatostatin receptor type 2 ligand SureCN4313450 family 2 25
5-hydroxytryptamine receptor 6 ligand SureCN5498885 family 5 4
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 2 0
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
Sigma non-opioid intracellular receptor 1 ligand 1'-[4-[1-(4-f... 2 0
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 6 ligand 1-[9-(2,5-dimethoxypheny... 2 0
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3
Glucocorticoid receptor ligand SureCN3894124 family 3 0
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-(1-methyl-4... 14 12
Lanosterol synthase inhibitor AGN-PC-07BZTX family 2 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 3
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00449984 CHEMBL593472 Bioactive SureCN4009503
CFAMM00449990 CHEMBL595689 Bioactive SureCN4013862
CFAMM00449983 CHEMBL593473 Bioactive SureCN4012454
CFAMM00449989 CHEMBL592506 Bioactive SureCN4013026
CFAMM00449988 CHEMBL595113 Bioactive SureCN4014656
CFAMM00449986 CHEMBL595344 Bioactive SureCN4014663
CFAMM00449985 CHEMBL594175 Bioactive SureCN4012266

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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