CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18964
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor (4aS,8aR)-4-(3,4-dimethoxyphenyl)-2-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-4a,5,8,8a-tetrahydrophthalazin-1-one;hydrochloride family
No. of Seeds 10 No. of Other Members 0
Family Centroid CFAMM00450046 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-specific 3',5'-cyclic phosphodiesterase 4D Binder Superfamily
Class Class 928

Cousin Family NamesSeedsMembers
Histamine H1 receptor and Histamine H3 receptor Ligand GSK1004... 13 18
Irdabisant family 49 53
Histamine H3 receptor Ligand A-349821 Family 49 228
Survival motor neuron protein inhibitor CHEMBL1303282 family 1 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 7 4
Histamine H1 receptor and Histamine H3 receptor ligand 4-[(4-m... 3 6
Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylp... 4 1
Histamine H3 receptor ligand 3-methyl-1-[4-(3-piperidin-1-ylpr... 6 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 7 13
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 1 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and Sodium-dep... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450053 CHEMBL595038 Bioactive (4aS,8aR)-4-(3,4-dimethoxyphenyl)-2-[[4-[(4-methylpiperazin-1-yl)methyl]phenyl]methyl]-4a,5,8,8a-tetrahydrophthalazin-1-one
CFAMM00450046 CHEMBL593656 Bioactive (4aS,8aR)-4-(3,4-dimethoxyphenyl)-2-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-4a,5,8,8a-tetrahydrophthalazin-1-one;hydrochloride
CFAMM00450052 CHEMBL593877 Bioactive SureCN4114163
CFAMM00450051 CHEMBL595272 Bioactive (4aS,8aR)-4-(3,4-dimethoxyphenyl)-2-[[2-(morpholin-4-ylmethyl)phenyl]methyl]-4a,5,6,7,8,8a-hexahydrophthalazin-1-one
CFAMM00450050 CHEMBL603626 Bioactive SureCN4110462
CFAMM00450049 CHEMBL592931 Bioactive SureCN4122253
CFAMM00450055 CHEMBL605096 Bioactive (1S,6R)-2-(3,4-dimethoxyphenyl)-4-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-3,4-diazabicyclo[4.2.0]oct-2-en-5-one
CFAMM00450048 CHEMBL596394 Bioactive SureCN4122695
CFAMM00450054 CHEMBL596447 Bioactive SureCN4122487
CFAMM00450047 CHEMBL595064 Bioactive SureCN4130701

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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