CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18966
Family Name Mitogen-activated protein kinase 14 inhibitor AGN-PC-07R77D family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00450063 Functional Category Bioactive
Superfamily Aurora kinase A Inhibitor ABT-348 Superfamily
Class Class 1250

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Hepatocyte growth factor receptor Ligand SGX523 Family 1 15
C-reactive protein Inhibitor ISIS-CRP Family 4 105
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 13 55
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Xanthine dehydrogenase/oxidase Inhibitor 3,5-di(pyridin-4-yl)-... 6 3
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 13 100
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BIUF2 family 25 11
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
5-hydroxytryptamine receptor 6 ligand 3-(benzenesulfonyl)-N,5-... 4 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 9 6
Glucose-dependent insulinotropic receptor ligand 4-({Ethyl-[1-... 6 12
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-cyc... 1 3
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
TGF-beta receptor type-1 ligand 3-(6-methylpyridin-2-yl)-N-phe... 21 0
Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... 5 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 1
Mitogen-activated protein kinase 14 inhibitor imidazole 81 family 2 1
Metabotropic glutamate receptor 2 ligand 3-(cyclopropylmethyl)... 1 1
Alpha-1A adrenergic receptor and D(2) dopamine receptor ligand... 1 0
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 1-met... 2 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
Metabotropic glutamate receptor 5 ligand SureCN4700553 family 1 0
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 3
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 0
Cyclooxygenase 2 and Prostaglandin G/H synthase 1 inhibitor Su... 2 1
Mitogen-activated protein kinase 14 inhibitor SureCN4205919 fa... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450061 CHEMBL609275 Bioactive AGN-PC-07R7TQ
CFAMM00450063 CHEMBL592978 Bioactive AGN-PC-07R77D

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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