CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18968
Family Name C-C chemokine receptor type 5 ligand 5-[(3aR,6aS)-2-[2-[1-(4,4-difluorocyclohexanecarbonyl)-3-phenylazetidin-3-yl]ethyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carbonyl]-4,6-dimethylpyridine-2-carbonitrile family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00450077 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 and C-C chemokine receptor type 5 Binder Superfamily
Class Class 173

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Substance-P receptor Ligand TAK-637 Family 18 63
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Glutamate receptor 1 Ligand Piriqualone Family 8 67
C-C chemokine receptor type 5 ligand [3-[2-[(3aS,6aR)-5-(4,6-d... 3 40
C-C chemokine receptor type 5 and C-C motif chemokine 5 ligand... 1 5
Metabotropic glutamate receptor 5 ligand AGN-PC-0A9SVV family 2 12
Melanin-concentrating hormone receptor 1 ligand N-[(3S)-1-[[(3... 2 0
Motilin receptor ligand SureCN2768052 family 3 0
Substance-P receptor ligand AGN-PC-004REJ family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450077 CHEMBL593027 Bioactive 5-[(3aR,6aS)-2-[2-[1-(4,4-difluorocyclohexanecarbonyl)-3-phenylazetidin-3-yl]ethyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carbonyl]-4,6-dimethylpyridine-2-carbonitrile
CFAMM00450076 CHEMBL593042 Bioactive 5-[(3aS,6aR)-2-[2-[1-(3,3-difluorocyclobutanecarbonyl)-3-phenylazetidin-3-yl]ethyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carbonyl]-4,6-dimethylpyridine-2-carbonitrile
CFAMM00450075 CHEMBL593046 Bioactive [3-[2-[(3aS,6aR)-5-[2,4-dimethyl-6-(trifluoromethyl)pyridine-3-carbonyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl]ethyl]-3-phenylazetidin-1-yl]-(4,4-difluorocyclohexyl)methanone
CFAMM00450074 CHEMBL593080 Bioactive [3-[2-[(3aS,6aR)-5-[2,4-dimethyl-6-(trifluoromethyl)pyridine-3-carbonyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl]ethyl]-3-phenylazetidin-1-yl]-(3,3-difluorocyclobutyl)methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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