CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18979
Family Name 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2A ligand AGN-PC-00IL3S family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00450155 Functional Category Bioactive
Superfamily Reverse transcriptase/RNaseH and Huntingtin Binder Superfamily
Class Class 873

Cousin Family NamesSeedsMembers
Melanin-concentrating hormone receptor 1 Ligand 8-sec-butoxy-q... 30 39
Melanin-concentrating hormone receptor 1 Ligand Gnf-pf-2322 Fa... 3 95
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 3


External ID

Functional Category

Molecule Name

CFAMM00450157 CHEMBL593545 Bioactive (8R)-8-(2-chlorophenoxy)-2-piperazin-1-yl-5,6,7,8-tetrahydroquinoline
CFAMM00450156 CHEMBL594251 Bioactive (7S)-7-(2-chlorophenoxy)-2-[(2R)-2-methylpiperazin-1-yl]-6,7-dihydro-5H-cyclopenta[b]pyridine
CFAMM00450155 CHEMBL595195 Bioactive AGN-PC-00IL3S
CFAMM00450154 CHEMBL595194 Bioactive (8S)-8-(2-chlorophenoxy)-2-piperazin-1-yl-5,6,7,8-tetrahydroquinoline
CFAMM00450159 CHEMBL609306 Bioactive SureCN3953981

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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