CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM18990
Family Name Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-3-[4-[4-[[(4-methylpyridin-2-yl)amino]methyl]-2-oxopyrrolidin-1-yl]phenyl]-2-[(2,4,6-trimethylbenzoyl)amino]propanoic acid family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00177019 Functional Category Bioactive
Superfamily Integrin beta-1 and Integrin alpha-5 Binder Superfamily
Class Class 639

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
Thromboxane A2 receptor Ligand Bibv 308 Family 14 40
JAK Inhibitor Momelotinib Family 33 83
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
XL-888 family 16 85
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Endothelin B receptor Ligand IRL-2500 Family 34 87
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 17 14
Cholecystokinin receptor type A ligand A-65186 family 2 6
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3888804 f... 11 13
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-quinolin... 6 8
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
C-C chemokine receptor type 5 ligand AC1LA25C family 3 6
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 13 3
B1 bradykinin receptor ligand AGN-PC-005XAO family 3 17
Glucagon receptor and Gastric inhibitory polypeptide receptor ... 1 3
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Aurora kinase A and Aurora kinase B inhibitor 4-fluoro-N-[4-[(... 6 1
C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-00IW9E f... 3 0
Integrin alpha-V and Integrin beta-6 inhibitor 3-[[2-[4-[(4-me... 4 3
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(2S)-4-methy... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 2 1
Integrin beta-1 and Integrin alpha-5 inhibitor SureCN14453385 ... 5 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-3-[[2-[(... 3 1
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1
Glucagon receptor ligand AGN-PC-0DAH9I family 1 0
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-3-[4-[5-[[... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23971 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543