CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM190
Family Name Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ligand AGN-PC-075IEA family
No. of Seeds 2 No. of Other Members 17
Family Centroid CFAMM00308716 Functional Category Bioactive
Superfamily Nuclear receptor ROR-gamma and 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Binder Superfamily
Class Class 2780

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Sodium channel protein type 10 subunit alpha Ligand A-803467 F... 2 81
Histamine H3 receptor Ligand A-317920 Family 9 240
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2... 4 31
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Alpha-1A adrenergic receptor Ligand RWJ-68141 Family 5 4
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Granulocyte colony-stimulating factor receptor Ligand N-(2-mor... 1 24
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 1 4
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 9 22
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 15 14
Phospholipase D1 and Phospholipase D2 inhibitor 4,5-dibromo-N-... 1 3
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 4
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 35
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 6
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(fur... 1 0
Bifunctional epoxide hydrolase 2 inhibitor 8-(2-methylfuran-3-... 2 1
Macrophage colony-stimulating factor 1 receptor ligand SureCN1... 6 1
Macrophage colony-stimulating factor 1 receptor ligand 5-cyano... 5 6
5-hydroxytryptamine receptor 1A ligand SureCN10513645 family 9 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 0
Mu-type opioid receptor ligand AGN-PC-00NCMO family 3 1
Mu-type opioid receptor ligand AGN-PC-00NCMG family 2 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 1 0
Huntingtin and Ras-related protein Rab-9A inhibitor CHEMBL1971... 1 1
Leukotriene A-4 hydrolase inhibitor SureCN5316998 family 1 0
Peroxisome proliferator-activated receptor alpha ligand AGN-PC... 1 0
Nuclear receptor ROR-gamma and Niemann-Pick C1 protein ligand ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308716 CHEMBL189787 Bioactive AGN-PC-075IEA

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27512 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543