CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19007
Family Name 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2A ligand SureCN3948121 family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00401871 Functional Category Bioactive
Superfamily Substance-P receptor and Nitric oxide synthase, brain Binder Superfamily
Class Class 2845

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
SB1518 family 7 103
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Melanin-concentrating hormone receptor 1 Ligand 8-sec-butoxy-q... 30 39
Melanin-concentrating hormone receptor 1 Ligand Gnf-pf-2322 Fa... 3 95
Metabotropic glutamate receptor 5 Ligand (3-ethoxy-pyridin-2-y... 3 12
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Fatty-acid amide hydrolase 1 Inhibitor BMS-1 Family 5 22
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 10 46
Metabotropic glutamate receptor 5 Ligand 7-(3,5-dimethoxypheny... 2 7
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Corticotropin-releasing factor receptor 1 ligand 6-ethyl-3-met... 6 10
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 15
Growth hormone secretagogue receptor type 1 ligand SureCN62436... 8 6
Beta-secretase 1 and Beta-secretase 2 inhibitor 7-fluoro-3-(5-... 2 7
Substance-P receptor and Sodium-dependent serotonin transporte... 11 6
Substance-P receptor and Sodium-dependent serotonin transporte... 11 4
Orexin receptor type 1 and Orexin receptor type 2 ligand (1R,2... 6 1
Nitric oxide synthase, inducible inhibitor SureCN2258300 family 2 24
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
Cannabinoid receptor 2 ligand SureCN1626177 family 1 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
TGF-beta receptor type-1 ligand SureCN373216 family 3 14
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 5 1
Acyl-CoA:cholesterol acyltransferase inhibitor 3-(2-chloro-6-m... 4 6
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 1 4
Glucokinase inhibitor 4-methyl-N-[3-phenylmethoxy-5-(pyridin-2... 1 8
Corticotropin-releasing factor receptor 1 ligand N-[(1R,2S)-2-... 3 0
TGF-beta receptor type-1 ligand 2wou family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450312 CHEMBL608116 Bioactive (7S)-7-(3-fluorophenoxy)-2-piperazin-1-yl-6,7-dihydro-5H-cyclopenta[b]pyridine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48711 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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