CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1901
Family Name Vasopressin V1b receptor ligand 2-[3-(3-chlorophenyl)-1-oxo-7-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide family
No. of Seeds 2 No. of Other Members 12
Family Centroid CFAMM00328679 Functional Category Bioactive
Superfamily Glycogen phosphorylase, muscle form Inhibitor PSN357 Superfamily
Class Class 913

Cousin Family NamesSeedsMembers
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Reverse transcriptase Inhibitor IDX899 Family 2 118
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
Ranirestat family 1 22
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Amine oxidase [flavin-containing] B Inhibitor Lazebemide Family 2 13
Transient receptor potential cation channel subfamily V member... 6 23
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Peroxisome proliferator-activated receptor gamma Ligand 2-chlo... 5 19
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 21
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Tyrosine-protein kinase ITK/TSK and Receptor-type tyrosine-pro... 1 0
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6R... 2 2
Metabotropic glutamate receptor 5 ligand [2-[6-(3-chlorophenyl... 1 1
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor 6-[(3... 10 0
Serine/threonine-protein kinase PLK1 and MAP kinase-activated ... 1 2
Histamine H1 receptor and Alpha-1B adrenergic receptor ligand ... 8 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Di... 2 3
Beta-secretase 1 and Potassium voltage-gated channel subfamily... 2 11
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 3 4
Coagulation factor X inhibitor ethyl (3R,4S)-3-[(3-chloro-1H-i... 5 0
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R96X family 7 1
Poly [ADP-ribose] polymerase 1 inhibitor SureCN3553433 family 22 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R9GP family 5 0
Metabotropic glutamate receptor 5 ligand [2-[6-(3-chlorophenyl... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00328679 CHEMBL1222839 Bioactive 2-[3-(3-chlorophenyl)-1-oxo-7-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
CFAMM00328684 CHEMBL1222909 Bioactive 2-[3-(3-chlorophenyl)-1-oxo-7-(4-pyrrolidin-1-ylpiperidin-1-yl)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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