CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19015
Family Name Cathepsin E and Cathepsin D inhibitor SureCN2529506 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00326873 Functional Category Bioactive
Superfamily Beta-1 adrenergic receptor and Beta-3 adrenergic receptor Binder Superfamily 2
Class Class 4220

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Beta-secretase 1 and Cathepsin D Inhibitor GRL-7234 Family 17 148
Beta-3 adrenergic receptor Ligand BMS-196085 Family 18 72
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Beta-secretase 1 and Cathepsin D inhibitor 3ixk family 2 9
Beta-secretase 1 and Cathepsin D inhibitor 3ixj family 10 21
Beta-secretase 1 inhibitor SureCN3599637 family 1 0
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide, 8... 4 15
Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN5224847 ... 3 24
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Beta-secretase 1 and Beta-secretase 2 inhibitor 3-(1,1-dioxoth... 6 2
Beta-secretase 1 inhibitor N-[(2S,3R)-1-(3,5-difluorophenyl)-3... 5 5
Beta-secretase 1 inhibitor 1-N-[(2S,3R)-1-(3,5-difluorophenyl)... 8 7
4-(4-methoxyphenyl)-2,4,5,10-tetrahydro-1H-pyrrolo[3,4-c][1,5]... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450329 CHEMBL595100 Bioactive SureCN2531564

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45567 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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