CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19031
Family Name Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ligand N-[3-[4-cyano-4-(2-methylphenyl)piperidin-1-yl]propyl]-2-hydroxy-2,2-bis(4-methylphenyl)acetamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00450376 Functional Category Bioactive
Superfamily C-C chemokine receptor type 1 and Sodium- Binder Superfamily
Class Class 3243

Cousin Family NamesSeedsMembers
Melanocortin receptor 4 and Melanocortin receptor 3 ligand Sur... 6 53
C-C chemokine receptor type 5 ligand N-[1-[[(3S,4R)-1-(cyclope... 1 16
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 10 20
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 13 0
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 4 3
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 1 0
Urotensin-2 inhibitor (2R)-N-[(1S)-3-(dimethylamino)-1-naphtha... 1 0


External ID

Functional Category

Molecule Name

CFAMM00450375 CHEMBL61643 Bioactive AGN-PC-074B7F
CFAMM00450376 CHEMBL59590 Bioactive N-[3-[4-cyano-4-(2-methylphenyl)piperidin-1-yl]propyl]-2-hydroxy-2,2-bis(4-methylphenyl)acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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