CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19042
Family Name Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R9GP family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00450441 Functional Category Bioactive
Superfamily Poly [ADP-ribose] polymerase 1 and Prothrombin Binder Superfamily
Class Class 1555

Cousin Family NamesSeedsMembers
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
Substance-P receptor Ligand TAK-637 Family 18 63
CP-18770 family 6 27
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Amine oxidase [flavin-containing] B Inhibitor Lazebemide Family 2 13
Transient receptor potential cation channel subfamily V member... 6 23
D(4) dopamine receptor Ligand ABT-670 Family 4 14
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Amine oxidase [flavin-containing] A Inhibitor N-benzyl-1h-pyrr... 12 46
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-... 3 5
Prothrombin inhibitor SureCN7371121 family 13 3
Vasopressin V1b receptor ligand 2-[3-(3-chlorophenyl)-1-oxo-7-... 2 12
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 21
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04SK7R family 3 3
Substance-K receptor ligand N-[1-[[(2R)-5-[4-(oxan-4-ylmethyl)... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6R... 2 2
Melanin-concentrating hormone receptor 1 ligand N-[(3S)-1-[[(3... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Di... 2 3
Probable G-protein coupled receptor 142 ligand (2S)-N-(2-oxo-5... 2 1
Beta-secretase 1 and Potassium voltage-gated channel subfamily... 2 11
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Beta-secretase 2 and Beta-secretase 1 inhibitor N-[3-[(1S,7S)-... 7 4
Neutrophil elastase inhibitor N-[(2S)-3-methyl-1-oxo-1-[(2S)-2... 4 4
Beta-secretase 1 and Beta-secretase 2 inhibitor N-[3-[(4S)-2-a... 6 4
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Metabotropic glutamate receptor 5 ligand AGN-PC-09SALK family 2 15
Substance-P receptor and Substance-K receptor ligand N-methyl-... 2 2
Dipeptidyl peptidase 4 inhibitor SureCN5777667 family 1 4
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R96X family 7 1
Poly [ADP-ribose] polymerase 1 inhibitor SureCN3553433 family 22 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450441 CHEMBL596933 Bioactive AGN-PC-07R9GP
CFAMM00450445 CHEMBL596720 Bioactive AGN-PC-07R9MZ
CFAMM00450444 CHEMBL599595 Bioactive AGN-PC-07R9GQ
CFAMM00450443 CHEMBL604291 Bioactive AGN-PC-07R9GO
CFAMM00450442 CHEMBL599793 Bioactive AGN-PC-07R9MY

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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