CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19047
Family Name Sodium-dependent serotonin transporter inhibitor SureCN5477150 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00450490 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin transporter Ligand Vilazodone Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
Indeglitazar family 3 39
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Platelet-derived growth factor receptor alpha and Platelet-der... 2 13
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 4 36
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 14
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 9 12
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 8 12
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
5-hydroxytryptamine receptor 2B and 5-hydroxytryptamine recept... 1 1
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 11 11
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 7 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 14 2
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 3 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Mu-type opioid receptor and Mu-type opioid receptor ligand (3S... 6 2
C-C chemokine receptor type 3 and Histamine H1 receptor ligand... 2 2
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 4 4
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 1 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
Substance-P receptor ligand SureCN2139814 family 7 7
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
RAC-alpha serine/threonine-protein kinase inhibitor Isoquinoli... 1 0
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 0
Glycogen synthase kinase-3 beta inhibitor bip-135 family 3 1
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 6 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 0
Protein kinase C theta type and Protein kinase C delta type in... 13 0
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4
Collagenase 3 inhibitor SureCN1316041 family 4 3
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3
ATP-binding cassette sub-family G member 2 inhibitor 5-[(4-bro... 1 1
Amino Acids and Derivatives Metabolite Flazine Family 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450492 CHEMBL603475 Bioactive AGN-PC-008XLF
CFAMM00450491 CHEMBL599112 Bioactive AGN-PC-00A2IM
CFAMM00450490 CHEMBL598742 Bioactive SureCN5477150

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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