CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19050
Family Name Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor 1-[6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-(3-fluorophenyl)urea family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00450500 Functional Category Bioactive
Superfamily Cyclin-A2 and Beta-lactamase Binder Superfamily
Class Class 5019

Cousin Family NamesSeedsMembers
Macrophage colony-stimulating factor 1 Inhibitor ABT-869 Family 8 56
Aurora kinase B and Aurora kinase A Inhibitor PHA-739358 Family 6 29
Cyclin-dependent kinase 2 Inhibitor N-(5-cyclopropyl-1h-pyrazo... 6 62
Aurora kinase B and Aurora kinase C Inhibitor PHA-680632 Family 5 72
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-0A9SI... 4 0
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 4
B1 bradykinin receptor ligand SureCN6045964 family 2 1
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(6-ph... 2 0
Neuropeptide Y receptor type 5 ligand N-[5-(4-chlorophenyl)-1H... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450500 CHEMBL596978 Bioactive 1-[6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-(3-fluorophenyl)urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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