CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19066
Family Name RAC-alpha serine/threonine-protein kinase and RAC-beta serine/threonine-protein kinase inhibitor AGN-PC-00EGH2 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00450549 Functional Category Bioactive
Superfamily Cannabinoid receptor 2 and RAC-beta serine/threonine-protein kinase Binder Superfamily
Class Class 4724

Cousin Family NamesSeedsMembers
Adenosine receptor A1 Ligand SLV320 Family 6 79
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Proto-oncogene tyrosine-protein kinase Src Inhibitor CGP-62464... 3 10
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 2 4
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
RAC-alpha serine/threonine-protein kinase inhibitor (2S)-3-ami... 2 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 0
Dihydrofolate reductase inhibitor 6-[[(4-chloronaphthalen-1-yl... 2 1
Cell division cycle 7-related protein kinase and Dual specific... 3 1
Mitogen-activated protein kinase 10 inhibitor CYCLOPROPYL-{4-[... 2 1
Nociceptin receptor and Mu-type opioid receptor ligand (1S,5S)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450549 CHEMBL597793 Bioactive AGN-PC-00EGH2

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26831 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543