CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19067
Family Name Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform inhibitor SureCN32342 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00163196 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Binder Superfamily
Class Class 1233

Cousin Family NamesSeedsMembers
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Serine/threonine-protein kinase mTOR Inhibitor AZD2014 Family 2 41
GDC-0349 family 44 77
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 37 10
JAK Inhibitor Momelotinib Family 33 83
Toll-like receptor 7 Ligand GS-9620 Family 2 4
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Amine oxidase [flavin-containing] A Inhibitor 3-benzyl-n-(2-mo... 2 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 25 4
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 5 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 7 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 7 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 46 9
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 10
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Epidermal growth factor receptor ligand pyrido[4,3-d]pyrimidin... 11 0
Glucosylceramidase and Alpha-galactosidase A inhibitor AC1NNEG... 4 5
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 8 4
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 3 3
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... 5 4
Ephrin type-B receptor 4 and Vascular endothelial growth facto... 1 4
Serine/threonine-protein kinase mTOR inhibitor SureCN2707225 f... 29 4
Serine/threonine-protein kinase mTOR inhibitor AGN-PC-088SNX f... 1 0
Transient receptor potential cation channel subfamily V member... 2 1
Transient receptor potential cation channel subfamily V member... 4 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 4
Serine/threonine-protein kinase mTOR inhibitor 2-[4-[4-[(3S)-3... 3 0
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Adenosine kinase inhibitor SureCN8248615 family 2 3
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 26 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 12 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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