CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19104
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-[(1R)-1'-(2-adamantylcarbamoyl)-4-bromospiro[1,2-dihydroindene-3,4'-piperidine]-1-yl]acetic acid family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00450687 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticosteroid 11-beta-dehydrogenase isozyme 2 Binder Superfamily 9
Class Class 5291

Cousin Family NamesSeedsMembers
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 3 1
Growth hormone-releasing hormone receptor ligand (1S)-1'-[(2R)... 7 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 7 0


External ID

Functional Category

Molecule Name

CFAMM00450688 CHEMBL605162 Bioactive AGN-PC-07NA3P
CFAMM00450687 CHEMBL601849 Bioactive 2-[(1R)-1'-(2-adamantylcarbamoyl)-4-bromospiro[1,2-dihydroindene-3,4'-piperidine]-1-yl]acetic acid
CFAMM00450686 CHEMBL602249 Bioactive 2-[(1S)-1'-(2-adamantylcarbamoyl)-4-bromospiro[1,2-dihydroindene-3,4'-piperidine]-1-yl]acetic acid
CFAMM00450689 CHEMBL606420 Bioactive AGN-PC-07RAIN

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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