CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1911
Family Name Serine/threonine-protein kinase Chk1 inhibitor N-[2-(dimethylamino)ethyl]-5-[(Z)-[6-(4-hydroxy-3-methoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]selenophene-2-carboxamide family
No. of Seeds 8 No. of Other Members 10
Family Centroid CFAMM00328780 Functional Category Bioactive with Natural Product
Superfamily Serine/threonine-protein kinase Chk1 and Transient receptor potential cation channel subfamily V member 1 Binder Superfamily
Class Class 3140

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
Serine/threonine-protein kinase Chk1 inhibitor N-[2-(dimethyla... 8 4
Serine/threonine-protein kinase Chk1 inhibitor 9-(4-amino-3-me... 3 7
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 13


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00328776 CHEMBL1223116 Bioactive 5-[(Z)-[6-(4-hydroxy-3-methoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-N-(2-pyrrolidin-1-ylethyl)selenophene-2-carboxamide
CFAMM00328790 CHEMBL1223182 Bioactive N-[2-(dimethylamino)ethyl]-5-[(Z)-[6-(4-hydroxy-3-methoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-2-methylselenophene-3-carboxamide
CFAMM00328775 CHEMBL1223115 Bioactive N-[2-(diethylamino)ethyl]-5-[(Z)-[6-(4-hydroxy-3-methoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]selenophene-2-carboxamide
CFAMM00328789 CHEMBL1223183 Bioactive N-[2-(diethylamino)ethyl]-5-[(Z)-[6-(4-hydroxy-3-methoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-2-methylselenophene-3-carboxamide
CFAMM00328788 CHEMBL1223184 Bioactive 5-[(Z)-[6-(4-hydroxy-3-methoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-2-methyl-N-(2-pyrrolidin-1-ylethyl)selenophene-3-carboxamide
CFAMM00328780 CHEMBL1223044 Bioactive N-[2-(dimethylamino)ethyl]-5-[(Z)-[6-(4-hydroxy-3-methoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]selenophene-2-carboxamide
CFAMM00328787 CHEMBL1223185 Bioactive 5-[(Z)-[6-(4-hydroxy-3-methoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-2-methyl-N-(2-morpholin-4-ylethyl)selenophene-3-carboxamide
CFAMM00328777 CHEMBL1223117 Bioactive 5-[(Z)-[6-(4-hydroxy-3-methoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-N-(2-morpholin-4-ylethyl)selenophene-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48694 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543