CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19137
Family Name RAC-alpha serine/threonine-protein kinase and Rho-associated protein kinase 1 inhibitor (6Z)-6-[5-[(2S)-2-amino-3-phenylpropoxy]-3-(3-methyl-2H-indazol-5-yl)-1H-pyridin-2-ylidene]-4-chlorocyclohexa-2,4-dien-1-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00450764 Functional Category Bioactive
Superfamily Fibroblast growth factor receptor Binder Superfamily
Class Class 1322

Cousin Family NamesSeedsMembers
PF-02545920 family 16 140
Fibroblast growth factor receptor Ligand LY2874455 Family 1 1
D(2) dopamine receptor Ligand SLV-314 Family 19 69
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 5
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL15681... 1 5
Somatostatin receptor type 2 ligand SureCN4317006 family 10 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 0
RAC-alpha serine/threonine-protein kinase and cAMP-dependent p... 3 0
Neuronal acetylcholine receptor subunit alpha-7 ligand 5-[6-[[... 1 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN4806204 f... 13 7
Serine/threonine-protein kinase Chk1 and Aurora kinase B inhib... 14 0
RAC-alpha serine/threonine-protein kinase and cAMP-dependent p... 2 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
B2 bradykinin receptor ligand SureCN13145573 family 7 6
B2 bradykinin receptor and Cytochrome P450 3A4 ligand SureCN15... 4 0


External ID

Functional Category

Molecule Name

CFAMM00450764 CHEMBL605733 Bioactive (6Z)-6-[5-[(2S)-2-amino-3-phenylpropoxy]-3-(3-methyl-2H-indazol-5-yl)-1H-pyridin-2-ylidene]-4-chlorocyclohexa-2,4-dien-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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