CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19161
Family Name Adenosine receptor A2a and Adenosine receptor A2b ligand (3R,4S,5R)-2-[6-amino-2-[(2E)-2-(cyclohexylmethylidene)hydrazinyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol family
No. of Seeds 7 No. of Other Members 3
Family Centroid CFAMM00450825 Functional Category Bioactive
Superfamily Adenosine receptor A2a and Adenosine receptor A2b Binder Superfamily
Class Class 172

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
HIV reverse transcriptase Inhibitor Abacavir Family 3 9
DNA Binder purine nucleoside Adenosine analog Nelarabine Family 2 10
Adenosine receptor A2a Ligand Regadenoson Family 10 22
Adenosine receptor A2a Ligand Atl-146e Family 33 94
P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Family 10 18
Adenosine receptor A3 Ligand CF101 Family 24 560
Adenosine receptor A2a Ligand MRE-0094 Family 10 108
Thyroid hormone receptor Ligand Dibrt Family 3 8
Equilibrative nucleoside/nucleobase transporter Inhibitor Nitr... 23 98
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 7 72
Adenosine receptor A1 and Adenosine receptor A2a Ligand GW-328... 26 94
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 21 57
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-[(4-... 15 9
Adenosine receptor A2a and Adenosine receptor A3 Ligand 2-(3''... 8 10
Adenosylhomocysteinase Inhibitor 4(z)-(5'-deoxyadenosin-5'-yli... 2 1
Inositol 1,4,5-trisphosphate receptor type 3 Ligand 5'-deoxy-5... 11 8
Adenosine receptor A3 and Adenosine receptor A1 ligand (1R,2R,... 10 15
Adenosine receptor A1 ligand CHEMBL2112106 family 7 7
Adenosine receptor A1 and Adenosine receptor A2a ligand (1S,3S... 3 0
Adenosine receptor A1 ligand 1-[6-(4-bicyclo[2.2.1]heptanylami... 3 0
Adenosine receptor A1 ligand CHEMBL258759 family 2 3
Adenosine receptor A1 and Adenosine receptor A2b ligand (2R,3R... 9 0
Adenosine receptor A2a and Adenosine receptor A2b ligand Cgs-2... 1 2
Adenosine receptor A2a and Adenosine receptor A2b ligand 3-[6-... 1 0
Adenosine receptor A3 and Adenosine receptor A2a ligand (2R,3R... 1 1
Putative Bioactive [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-di... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450829 CHEMBL611607 Bioactive (3R,4S,5R)-2-[6-amino-2-[(2E)-2-(cyclohex-3-en-1-ylmethylidene)hydrazinyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00450828 CHEMBL611917 Bioactive (3R,4S,5R)-2-[6-amino-2-[(2E)-2-[(6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl)methylidene]hydrazinyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00450833 CHEMBL607796 Bioactive (3R,4S,5R)-2-[6-amino-2-[(2E)-2-(cyclohexen-1-ylmethylidene)hydrazinyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00450826 CHEMBL608663 Bioactive (3R,4S,5R)-2-[6-amino-2-[(2E)-2-(2-cyclohexylethylidene)hydrazinyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00450832 CHEMBL610443 Bioactive (3R,4S,5R)-2-[6-amino-2-[(2E)-2-(3-bicyclo[2.2.1]hept-2-enylmethylidene)hydrazinyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00450825 CHEMBL609256 Bioactive (3R,4S,5R)-2-[6-amino-2-[(2E)-2-(cyclohexylmethylidene)hydrazinyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CFAMM00450830 CHEMBL608966 Bioactive (3R,4S,5R)-2-[6-amino-2-[(2E)-2-(3-cyclohexylpropylidene)hydrazinyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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