CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19166
Family Name Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase inhibitor [(2R,3S,4R,5R)-5-[6-amino-2-(4-hexyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine family
No. of Seeds 30 No. of Other Members 0
Family Centroid CFAMM00450872 Functional Category Bioactive
Superfamily Beta-1 adrenergic receptor Ligand Cgp 20712a Superfamily
Class Class 1256

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 21 57
Enterobactin synthase component E inhibitor [(2,3-dihydroxyben... 1 8
Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) ... 24 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450854 CHEMBL611783 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-pyridin-2-yltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450867 CHEMBL612049 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-heptyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450860 CHEMBL612057 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(cyclohexen-1-yl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450873 CHEMBL611776 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-phenyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450866 CHEMBL612048 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-cyclopropyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450853 CHEMBL611782 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(4-hydroxyphenyl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450879 CHEMBL609105 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-cyclopentyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450859 CHEMBL612037 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-octyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450872 CHEMBL611772 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-hexyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450852 CHEMBL608840 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-propyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450865 CHEMBL608839 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(2-methylphenyl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450878 CHEMBL609103 Bioactive N,N-diethylethanamine;ethyl 1-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(2-hydroxybenzoyl)sulfamoyloxymethyl]oxolan-2-yl]purin-2-yl]triazole-4-carboxylate
CFAMM00450858 CHEMBL612052 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(3-hydroxyphenyl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450871 CHEMBL612044 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-dodecyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450851 CHEMBL608842 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(3-methylphenyl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450864 CHEMBL608838 Bioactive N,N-diethylethanamine;methyl 1-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(2-hydroxybenzoyl)sulfamoyloxymethyl]oxolan-2-yl]purin-2-yl]triazole-4-carboxylate
CFAMM00450877 CHEMBL609100 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-pyridin-4-yltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450857 CHEMBL611785 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(4-methylphenyl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450870 CHEMBL612042 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-decyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450850 CHEMBL608843 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(2-methylpropyl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450863 CHEMBL611767 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-tert-butyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450876 CHEMBL609101 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(2-aminophenyl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450856 CHEMBL611784 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-pentyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450869 CHEMBL612041 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(4-aminophenyl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450862 CHEMBL611766 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-cyclohexyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450875 CHEMBL611774 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(hydroxymethyl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450855 CHEMBL611780 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-pyridin-3-yltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450868 CHEMBL612040 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(2-hydroxyphenyl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450861 CHEMBL612051 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-(4-butyltriazol-1-yl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine
CFAMM00450874 CHEMBL611775 Bioactive [(2R,3S,4R,5R)-5-[6-amino-2-[4-(3-aminophenyl)triazol-1-yl]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate;N,N-diethylethanamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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