CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19174
Family Name Caspase-1 inhibitor (2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-methylbutanoyl]amino]propanoyl]amino]butanedioic acid family
No. of Seeds 1 No. of Other Members 9
Family Centroid CFAMM00450910 Functional Category Bioactive with Human Metabolite & Natural Product
Superfamily Caspase-1 and Neprilysin Binder Superfamily
Class Class 1590

Cousin Family NamesSeedsMembers
Aspartate transcarbamoylase catalytic subunit PyrB Inhibitor N... 1 1
D-alanyl-D-alanine carboxypeptidase Inhibitor Glycyl-l-alpha-a... 5 89
Dihydroorotase, putative Inhibitor N-carbamoyl-l-aspartate Family 2 8
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Alp... 4 18
Caspase-3 inhibitor 5-fluoro-3-[[(2S)-2-(methoxycarbonylamino)... 3 2
Prelamin-A/C and DNA-(apurinic or apyrimidinic site) lyase inh... 1 2
Nitric oxide synthase, brain and Nitric oxide synthase, endoth... 1 7
Amino Acids and Derivatives Metabolite 2-Methylbutyrylglycine ... 2 0
Amino Acids and Derivatives Metabolite L-beta-aspartyl-L-aspar... 1 6
Peptides Metabolite Serinyl-Asparagine Family 2 11
Peptides Metabolite L-prolyl-L-glycine Family 1 3
Amino Acids and Derivatives Metabolite L-2-Amino-3-(oxalylamin... 2 1
2-[(2-azaniumylacetyl)amino]pentanoate NP 2-(2-aminoacetamido)... 3 2


External ID

Functional Category

Molecule Name

CFAMM00450910 CHEMBL61023 Bioactive (2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-methylbutanoyl]amino]propanoyl]amino]butanedioic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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