CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19188
Family Name Sterol O-acyltransferase 1 inhibitor SureCN7073167 family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00450950 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 2C Ligand 6-chloro-n-(pyridin-3-yl)indoline-1-carboxamide Superfamily
Class Class 88

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Sertindole Family 3 173
Transient receptor potential cation channel subfamily V member... 15 158
Transient receptor potential cation channel subfamily V member... 16 295
Amg 423 family 7 47
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-(3-cyano-... 2 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 9
Transient receptor potential cation channel subfamily V member... 3 1
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 1 13
Tyrosine-protein kinase ABL1 and Mitogen-activated protein kin... 1 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 8
Prostaglandin E synthase and Aldo-keto reductase family 1 memb... 3 12
Mitogen-activated protein kinase 14 inhibitor 4-(2-chloro-4-fl... 6 7
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 4
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
Macrophage colony-stimulating factor 1 receptor and Vascular e... 2 3
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 2 0
Cholesteryl ester transfer protein inhibitor 1-[(1S)-1-(5-chlo... 1 4
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 7 2
Proto-oncogene tyrosine-protein kinase Src and Fibroblast grow... 3 4
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... 9 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 1 0
Transient receptor potential cation channel subfamily V member... 2 0
Reverse transcriptase/RNaseH inhibitor (4s)-6-chloro-4-cyclopr... 5 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450955 CHEMBL63019 Bioactive 1-[7-chloro-6-methyl-4-(2-methylphenyl)quinolin-3-yl]-3-(2,4-difluorophenyl)urea
CFAMM00450953 CHEMBL64976 Bioactive Tmp 153
CFAMM00450950 CHEMBL62063 Bioactive SureCN7073167
CFAMM00450949 CHEMBL62332 Bioactive SureCN9162892

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27291 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543