CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19193
Family Name Coagulation factor X and Prothrombin inhibitor SureCN7690879 family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00450961 Functional Category Bioactive
Superfamily Coagulation factor X and cAMP-specific 3',5'-cyclic phosphodiesterase 4B Binder Superfamily
Class Class 8

Cousin Family NamesSeedsMembers
D(3) dopamine receptor Ligand SB-277011 Family 13 178
JAK Inhibitor Momelotinib Family 33 83
XL-888 family 16 85
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Cyclin-dependent kinase 4 Inhibitor 1-(9-oxo-9h-fluoren-4-yl)-... 3 5
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Transient receptor potential cation channel subfamily V member... 6 23
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Tubulin beta chain Inhibitor 2-m-tolyl-1h-[1,8]naphthyridin-4-... 5 2
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 1 7
Coagulation factor X inhibitor 1-amino-N-[(1R)-2-[4-(4-fluoro-... 2 7
Coagulation factor X and Trypsin-1 inhibitor 2-(5-carbamimidoy... 5 2
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-075TBZ family 2 2
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 5
Aurora kinase A and Aurora kinase B inhibitor 4-fluoro-N-[4-[(... 6 1
Serine/threonine-protein kinase SMG1 and Serine/threonine-prot... 10 0
Coagulation factor X inhibitor (Z)-3-(3-carbamimidoylphenyl)-2... 2 2
Coagulation factor X and Trypsin-1 inhibitor SureCN6166035 family 1 2
Cannabinoid receptor 2 ligand N-isoquinolin-1-yl-4-methyl-3-pi... 1 0
Coagulation factor X inhibitor (E)-2-fluoro-3-[3-(N'-methylcar... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00450959 CHEMBL63088 Bioactive SureCN4352253
CFAMM00450961 CHEMBL62288 Bioactive SureCN7690879
CFAMM00450960 CHEMBL63041 Bioactive SureCN7681940

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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