CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19221
Family Name Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)-7-N-hydroxy-6-(2-methylpropyl)-5-oxo-3-N-pyridin-2-yl-12-oxa-4-azabicyclo[11.2.2]heptadeca-1(15),13,16-triene-3,7-dicarboxamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00451047 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and Peptidyl-prolyl cis-trans isomerase A Binder Superfamily
Class Class 1612

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma Ligand Piogli... 2 29
Histamine H1 receptor Ligand Mepyramine Family 5 65
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Smoothened homolog Inhibitor LDE225 Family 3 76
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
Chymase Inhibitor NK3201 Family 1 0
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 3
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 4 3
Renin inhibitor (1R,5S)-N-cyclopropyl-N-[(2-methoxy-3-methylpy... 2 3
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-prote... 2 0
Integrin alpha-V and Integrin beta-5 inhibitor SureCN2491273 f... 11 10
Integrin beta-3 and Integrin alpha-V inhibitor (3S,7S)-7-hydro... 5 1
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(4-fluo... 7 1
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-03OERH f... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 12 2
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Interstitial collagenase and Matrilysin inhibitor (3S,6R,7S)-N... 2 4
Peroxisome proliferator-activated receptor gamma and Cytochrom... 1 1
P2X purinoceptor 7 inhibitor N-[2,2-dichloro-1-[(Z)-[(cyanoami... 1 2
Renin inhibitor SureCN7300793 family 2 5
Pol polyprotein inhibitor N-benzyl-2,2-difluoro-4-[[(2S)-3-met... 1 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN244675 fa... 1 0
Farnesyl pyrophosphate synthase inhibitor [phosphono-[[4-(4-pr... 6 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 2
5-(4-methoxyphenyl)-4-oxo-1H-pyrido[2,3-d]pyrimidin-2-olate NP... 1 0
4-[(4-pyridin-1-ium-2-ylpiperazin-1-yl)methyl]chromen-2-one NP... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00451047 CHEMBL65159 Bioactive (3S,6R,7S)-7-N-hydroxy-6-(2-methylpropyl)-5-oxo-3-N-pyridin-2-yl-12-oxa-4-azabicyclo[11.2.2]heptadeca-1(15),13,16-triene-3,7-dicarboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27634 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543