CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19222
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor (2S)-2-[[(2S,4S)-1-[(5R)-5-amino-6-sulfanylhexanoyl]-4-phenoxypyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoic acid;2,2,2-trifluoroacetic acid family
No. of Seeds 1 No. of Other Members 9
Family Centroid CFAMM00451056 Functional Category Bioactive
Superfamily Penicillin binding protein Inhibitor Penicillin V Superfamily
Class Class 589

Cousin Family NamesSeedsMembers
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Penicillin binding protein Inhibitor Penicillin V Family 1 25
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Plasmepsin-2 Inhibitor KNI-727 Family 3 37
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 4
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(4S)-3... 3 24
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6453971 f... 3 4
Angiotensin-converting enzyme and Neprilysin inhibitor (2S,5R)... 15 3
Angiotensin-converting enzyme 2 and Neprilysin inhibitor (2S)-... 6 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2-me... 4 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6429531 f... 2 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Angiotensin-converting enzyme inhibitor (2S,4S)-1-[(2S)-2-meth... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00451056 CHEMBL65257 Bioactive (2S)-2-[[(2S,4S)-1-[(5R)-5-amino-6-sulfanylhexanoyl]-4-phenoxypyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoic acid;2,2,2-trifluoroacetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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