CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19231
Family Name 72 kDa type IV collagenase and Interstitial collagenase inhibitor (3S,6R,7S)-7-N-hydroxy-6-(2-methylpropyl)-5-oxo-3-N-[2-(4-sulfamoylphenyl)ethyl]-12-oxa-4-azabicyclo[11.2.2]heptadeca-1(15),13,16-triene-3,7-dicarboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00183221 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase and Growth hormone secretagogue receptor type 1 Binder Superfamily
Class Class 3079

Cousin Family NamesSeedsMembers
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Interstitial collagenase Inhibitor N-hydroxycarbamoylmethyl-4-... 5 24
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Oxytocin receptor Ligand [mpa1, D-tyr(et)2, D-tic7]ot Family 43 26
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 7
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)... 2 2
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Collagenase 3 and Interstitial collagenase inhibitor N-hydroxy... 8 4
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4Z)... 17 0
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
72 kDa type IV collagenase and Matrix metalloproteinase-25 inh... 1 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 4 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 0
Pol polyprotein inhibitor MDL 74538 family 11 1
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
Macrophage metalloelastase and Collagenase 3 inhibitor (2S)-N-... 2 2
Calpain-1 catalytic subunit inhibitor 2-ethyl-1,1-dioxo-N-[(2S... 4 30
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 5 2
Follicle-stimulating hormone receptor ligand SureCN6140614 family 2 8
Cathepsin S and Cathepsin L1 inhibitor benzyl N-[(2S)-1-oxo-1-... 2 2
Pol polyprotein inhibitor (3S)-N-tert-butyl-2-[(2R)-2-[(3S,6S,... 3 1
Stromelysin-1 and Interstitial collagenase inhibitor (2R)-2-[4... 4 1
Neutrophil collagenase and Matrix metalloproteinase-9 inhibito... 1 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27430 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543