CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19234
Family Name Bifunctional dihydrofolate reductase-thymidylate synthase inhibitor AGN-PC-074P6Q family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00451125 Functional Category Bioactive
Superfamily Bifunctional dihydrofolate reductase-thymidylate synthase and Polyamine oxidase Binder Superfamily
Class Class 655

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Proguanil Family 8 46
5-hydroxytryptamine receptor 5A Ligand N,4-dimethyl-3,4-dihydr... 8 51
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 14 78
Urease subunit alpha Inhibitor 3-(4-bromophenyl)-1,1-dimethylt... 1 3
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 8
ATP-binding cassette sub-family C member 9 and ATP-sensitive i... 2 3


External ID

Functional Category

Molecule Name

CFAMM00451119 CHEMBL6741 Bioactive GNF-Pf-1945
CFAMM00451126 CHEMBL93748 Bioactive 1-(4-bromophenyl)-2-methyl-2H-1,3,5-triazine-4,6-diamine
CFAMM00451125 CHEMBL90461 Bioactive AGN-PC-074P6Q
CFAMM00451124 CHEMBL93888 Bioactive AGN-PC-074PAY
CFAMM00451121 CHEMBL93893 Bioactive 1-(4-bromophenyl)-2-phenyl-2H-1,3,5-triazine-4,6-diamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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