CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19237
Family Name Delta-type opioid receptor and Mu-type opioid receptor ligand N-ethyl-N-(2-hydroxyethyl)-4-[phenyl-[8-(2-phenylethyl)-8-azabicyclo[3.2.1]octan-3-ylidene]methyl]benzamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00171836 Functional Category Bioactive
Superfamily Kappa-type opioid receptor Ligand Asimadoline Superfamily
Class Class 1062

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Diet... 29 276
DNA Binder Procarbazine Family 8 358
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Kappa-type opioid receptor Ligand Asimadoline Family 14 54
Bavisant family 9 65
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Farnesyltransferase beta subunit, putative and Protein farnesy... 6 3
Histone deacetylase 1 Inhibitor 8-(3-benzoyl-ureido)-octanoic ... 7 13
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Acetyl-CoA carboxylase 1 and Acetyl-CoA carboxylase 2 Inhibito... 1 0
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
D(2) dopamine receptor and D(3) dopamine receptor Ligand ST-19... 5 27
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-benza... 3 9
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Cathepsin K inhibitor [(3S)-4,4-dimethyl-1-(naphthalene-2-carb... 4 9
Substance-K receptor ligand 4-(4-methylphenyl)-N-[1-[[(2S)-5-[... 6 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 7
C-C chemokine receptor type 5 ligand AC1L9USC family 3 2
Kappa-type opioid receptor ligand 6-[2-oxo-2-[(2S)-2-(pyrrolid... 6 4
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 3 1
Acetylcholinesterase inhibitor 5-benzoyl-2-[2-(1-benzylpiperid... 2 3
Neuromedin-K receptor ligand SureCN2477089 family 2 4
Kappa-type opioid receptor and Delta-type opioid receptor liga... 9 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 9 0
Dipeptidyl peptidase 4 inhibitor 4-cyano-N-[4-[(2S)-2-cyanopyr... 1 1
Melanin-concentrating hormone receptor 1 and Cytochrome P450 2... 3 4
Kappa-type opioid receptor ligand 1-[4-acetyl-2-[[(3S)-3-hydro... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 1
Follicle-stimulating hormone receptor ligand N-[[3-[4-[[(2S,5S... 7 0
Kappa-type opioid receptor ligand SureCN5629426 family 3 2
Plasmepsin-2 inhibitor SureCN8292428 family 1 2
Kappa-type opioid receptor ligand 3-[3-(hydroxymethyl)phenyl]-... 1 0
C-C chemokine receptor type 5 ligand N-benzyl-N-[(3R)-1-[(1S,5... 1 3
Muscarinic acetylcholine receptor M3 ligand N-[[4-fluoro-3-[3-... 3 0
Muscarinic acetylcholine receptor M2 ligand 3-[(1Z)-1-benzylid... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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