CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19264
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 1D ligand SureCN8887262 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00288491 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin transporter Binder Superfamily
Class Class 1116

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
D(1A) dopamine receptor ligand ergot alkaloid Methylergonovine... 22 170
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
D(2) dopamine receptor Ligand Sertindole Family 3 173
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
E7820 family 9 56
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
Nicotinic acetylcholine receptor Ligand Epibatidine Family 36 19
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... 10 43
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 3 15
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
5-hydroxytryptamine receptor 6 Ligand E-6837 Family 22 44
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(thiophen... 9 66
Trypsin Inhibitor 1-benzyl-1h-indole-5-carboxamidine Family 4 3
Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... 7 7
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 4 10
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 2 4
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 10 18
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 6
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Protein kinase C theta type and Protein kinase C delta type in... 7 17
Protein kinase C theta type and Protein kinase C delta type in... 16 8
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 3
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
Sodium-dependent serotonin transporter inhibitor SureCN6087392... 1 1
Sodium-dependent serotonin transporter inhibitor SureCN6087152... 1 0
D(4) dopamine receptor and D(1A) dopamine receptor ligand 2-[[... 5 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 1
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 10 9
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 9 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 18 3
Glucocorticoid receptor and Androgen receptor ligand AGN-PC-0A... 3 0
Sodium-dependent serotonin transporter inhibitor 3-[[(3S)-1-az... 1 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
CGMP-dependent protein kinase inhibitor AGN-PC-075XII family 25 7
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 0
CGMP-dependent protein kinase inhibitor methyl 2-[[4-[5-(4-flu... 6 1
CGMP-dependent protein kinase inhibitor AGN-PC-075INU family 1 1
Protein kinase C theta type and Protein kinase C delta type in... 4 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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