CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19277
Family Name [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial and [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial inhibitor SureCN5737441 family
No. of Seeds 4 No. of Other Members 31
Family Centroid CFAMM00451262 Functional Category Bioactive
Superfamily [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial and [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial Binder Superfamily 2
Class Class 5305

Cousin Family NamesSeedsMembers
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 5 10
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[2-[... 1 4
Metabotropic glutamate receptor 5 and Beta-lactamase ligand 2-... 3 1
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor AGN-PC... 1 0
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme ... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00451246 CHEMBL73068 Bioactive (2R)-N-[2-chloro-4-(cyclopropylmethylsulfamoyl)phenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
CFAMM00451272 CHEMBL73204 Bioactive (2R)-N-[4-[(3-aminocyclohexyl)sulfamoyl]-2-chlorophenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
CFAMM00451257 CHEMBL75821 Bioactive SureCN5747061
CFAMM00451262 CHEMBL74582 Bioactive SureCN5737441

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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