CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1928
Family Name Serine/threonine-protein kinase Chk1 inhibitor N-[2-(dimethylamino)ethyl]-5-[(Z)-[6-(4-hydroxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]selenophene-2-carboxamide family
No. of Seeds 8 No. of Other Members 4
Family Centroid CFAMM00328904 Functional Category Bioactive with Natural Product
Superfamily Serine/threonine-protein kinase Chk1 and Transient receptor potential cation channel subfamily V member 1 Binder Superfamily
Class Class 3140

Cousin Family NamesSeedsMembers
High affinity nerve growth factor receptor and RAF proto-oncog... 3 29
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Transient receptor potential cation channel subfamily V member... 2 29
Serine/threonine-protein kinase Chk1 inhibitor N-[2-(dimethyla... 8 10
G-protein coupled receptor 55 and Cannabinoid receptor 1 ligan... 1 1


External ID

Functional Category

Molecule Name

CFAMM00328908 CHEMBL1223477 Bioactive 5-[(Z)-[6-(4-hydroxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-2-methyl-N-[2-(oxazinan-2-yl)ethyl]selenophene-3-carboxamide
CFAMM00328901 CHEMBL1223338 Bioactive N-[2-(diethylamino)ethyl]-5-[(Z)-[6-(4-hydroxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]selenophene-2-carboxamide
CFAMM00328906 CHEMBL1223409 Bioactive 5-[(Z)-[6-(4-hydroxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-2-methyl-N-(2-pyrrolidin-1-ylethyl)selenophene-3-carboxamide
CFAMM00328905 CHEMBL1223408 Bioactive N-[2-(diethylamino)ethyl]-5-[(Z)-[6-(4-hydroxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-2-methylselenophene-3-carboxamide
CFAMM00328904 CHEMBL1223337 Bioactive N-[2-(dimethylamino)ethyl]-5-[(Z)-[6-(4-hydroxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]selenophene-2-carboxamide
CFAMM00328910 CHEMBL1223407 Bioactive N-[2-(dimethylamino)ethyl]-5-[(Z)-[6-(4-hydroxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-2-methylselenophene-3-carboxamide
CFAMM00328903 CHEMBL1223340 Bioactive 5-[(Z)-[6-(4-hydroxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-N-[2-(oxazinan-2-yl)ethyl]selenophene-2-carboxamide
CFAMM00328902 CHEMBL1223339 Bioactive 5-[(Z)-[6-(4-hydroxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-N-(2-pyrrolidin-1-ylethyl)selenophene-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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