CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19290
Family Name Trypsin-1 inhibitor N-[7-amino-1-[2-(4-carbamoylphenyl)ethylamino]-1,2-dioxoheptan-3-yl]-2-(4-methoxyphenyl)-8-(2-methylpropyl)-1,3-dioxo-5,8-dihydro-[1,2,4]triazolo[1,2-a]pyridazine-5-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00451318 Functional Category Bioactive
Superfamily Trypsin-1 and Disintegrin Binder Superfamily
Class Class 1624

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Substance-K receptor Ligand MEN-14933 Family 13 154
Coagulation factor X Inhibitor BMS-269223 Family 15 58
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEH3 family 3 16
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 0
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Glucagon receptor and Gastric inhibitory polypeptide receptor ... 3 11
Bifunctional epoxide hydrolase 2 inhibitor 8-(2,6-difluorobenz... 4 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 11 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00451318 CHEMBL73970 Bioactive N-[7-amino-1-[2-(4-carbamoylphenyl)ethylamino]-1,2-dioxoheptan-3-yl]-2-(4-methoxyphenyl)-8-(2-methylpropyl)-1,3-dioxo-5,8-dihydro-[1,2,4]triazolo[1,2-a]pyridazine-5-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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