CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1932
Family Name 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2A ligand SureCN8640337 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00328926 Functional Category Bioactive
Superfamily Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily 2
Class Class 1973

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
D(2) dopamine receptor Ligand Sertindole Family 3 173
Gamma-aminobutyric acid A receptor Ligand Bromazepam Family 2 60
Transient receptor potential cation channel subfamily V member... 15 158
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Growth hormone receptor Ligand EP-51216 Family 34 390
Amg 423 family 7 47
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
Lethal factor Inhibitor GM6001 Family 50 435
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Dihydroorotate dehydrogenase Inhibitor Nsc 665564 Family 2 83
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 3 15
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-(3-cyano-... 2 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 4 33
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C9 inhib... 1 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 10 1
5-hydroxytryptamine receptor 1A ligand 2-[4-(quinolin-2-ylmeth... 2 91
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 8
Prothrombin and Trypsin-1 inhibitor 2-[6-methyl-2-oxo-3-(2-pyr... 4 2
C-X-C chemokine receptor type 3 ligand (6aR,9R)-N-phenyl-4-(2-... 5 0
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
Macrophage colony-stimulating factor 1 receptor and Vascular e... 2 3
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 3 1
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 2 0
Glucocorticoid receptor ligand 3,3,3-trifluoro-N-[(3S)-3-[1-(4... 10 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 2 2
C-C chemokine receptor type 3 and Cytochrome P450 2D6 ligand 1... 5 0
CGMP-dependent protein kinase inhibitor 1-[4-acetyl-3-[[4-[5-(... 2 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 1 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 3 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 4
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... 9 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 1 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN6080935 f... 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor AGN-PC-00GCQW f... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00328926 CHEMBL12235 Bioactive SureCN8640337

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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