CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19358
Family Name Prothrombin and Trypsin-1 inhibitor 2-[(2S)-4-benzyl-2-(naphthalen-2-ylmethyl)-3,6-dioxopiperazin-1-yl]-N-[(2S)-3-(1-carbamimidoylpiperidin-3-yl)-1-oxo-1-(1,3-thiazol-2-yl)propan-2-yl]acetamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00451561 Functional Category Bioactive
Superfamily Prothrombin and Trypsin-1 Binder Superfamily 2
Class Class 2352

Cousin Family NamesSeedsMembers
Tubulin beta chain Inhibitor DOLASTATIN-10 Family 4 93
Coagulation factor X Inhibitor Phso2-gly-(me-gly)-arg-(2-thiaz... 32 62
Fatty-acid amide hydrolase 1 Inhibitor 7-phenyl-1-(thiazol-2-y... 4 5
Prothrombin inhibitor (3R,6R,8aS)-N-[5-(diaminomethylideneamin... 4 1
Prothrombin inhibitor (6S,8aS)-N-[5-(diaminomethylideneamino)-... 12 10
Prothrombin inhibitor N-[(2S)-3-[(3S)-1-carbamimidoylpiperidin... 4 10
Coagulation factor XI and Prothrombin inhibitor alpha-ketothia... 5 2
Cationic trypsin and Prothrombin inhibitor benzyl N-[(2R)-1-[(... 2 6
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-2-amin... 1 0
Coagulation factor X and Prothrombin inhibitor (2S)-2-(benzyls... 4 4
Coagulation factor X and Prothrombin inhibitor AGN-PC-0754DR f... 2 2
Coagulation factor X and Prothrombin inhibitor 2-[(3S)-3-benzy... 7 0
Coagulation factor X and Prothrombin inhibitor N-[5-(diaminome... 2 0
Prothrombin inhibitor (3R,6S,8aS)-N-[5-(diaminomethylideneamin... 2 3
Coagulation factor X and Prothrombin inhibitor SureCN7377461 f... 4 0
Coagulation factor X and Prothrombin inhibitor 2-[4-(5-chloron... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00451561 CHEMBL79245 Bioactive 2-[(2S)-4-benzyl-2-(naphthalen-2-ylmethyl)-3,6-dioxopiperazin-1-yl]-N-[(2S)-3-(1-carbamimidoylpiperidin-3-yl)-1-oxo-1-(1,3-thiazol-2-yl)propan-2-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27423 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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