CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19362
Family Name Pol polyprotein inhibitor N-benzyl-2,2-difluoro-4-[[(2S)-3-methyl-2-(3-pyridin-3-ylpropanoylamino)butanoyl]amino]-3-oxo-5-(4-phenylmethoxyphenyl)pentanamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00451578 Functional Category Bioactive
Superfamily Chymase and Liver carboxylesterase 1 Binder Superfamily
Class Class 963

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Indinavir Family 36 211
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
Chymase Inhibitor NK3201 Family 1 0
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Fatty-acid amide hydrolase 1 Inhibitor Pyridin-3-yl 4-butoxybe... 10 5
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Neutrophil elastase inhibitor phenyl N-[(2S)-1-[(2S)-2-[[(3S)-... 2 0
Pol polyprotein inhibitor pyridin-2-ylmethyl N-[(2R)-1-[[(2S,3... 15 8
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 8 8
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 4 2
Renin inhibitor (1R,5S)-N-cyclopropyl-N-[(2-methoxy-3-methylpy... 2 3
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 4 4
Prostaglandin D2 receptor 2 ligand 2-[1-[4-[(4-methoxybenzoyl)... 2 2
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 3 1
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Plasmepsin-2 and Cathepsin D inhibitor 4-[4-[[(2S,3S)-1-[[(3S,... 3 0
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 2
Pol polyprotein inhibitor Palinavir deriv. 13 family 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 0
Renin inhibitor SureCN7300793 family 2 5
Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)... 2 2
Prothrombin inhibitor N-[(2S)-3-(4-aminophenyl)-1-[4-(2-fluoro... 7 4
Lysophosphatidic acid receptor 1 and Lysophosphatidic acid rec... 3 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00451578 CHEMBL79362 Bioactive N-benzyl-2,2-difluoro-4-[[(2S)-3-methyl-2-(3-pyridin-3-ylpropanoylamino)butanoyl]amino]-3-oxo-5-(4-phenylmethoxyphenyl)pentanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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