CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1938
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-[(1R,5S)-3-azabicyclo[3.1.0]hexan-1-yl]phenyl]-4-butylbenzenesulfonamide family
No. of Seeds 8 No. of Other Members 10
Family Centroid CFAMM00328991 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)phenyl)benzenesulfonamide Superfamily
Class Class 2249

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Sodium-dependent noradrenaline transporter inhibitor 3-[1-(2-f... 2 13
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 9 26
Mu-type opioid receptor and Mu-type opioid receptor ligand N-[... 2 4
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 6 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(4-... 2 10
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
Growth hormone secretagogue receptor type 1 ligand SureCN47963... 3 3
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor aryls... 2 3
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 3 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Neutrophil collagenase and Stromelysin-1 inhibitor [(1R)-2-met... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 4 1
Orexin receptor type 2 ligand SureCN1039013 family 1 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-014RDG family 1 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0


External ID

Functional Category

Molecule Name

CFAMM00329007 CHEMBL1224639 Bioactive N-[4-[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-1-yl]phenyl]-4-propan-2-ylbenzenesulfonamide
CFAMM00328991 CHEMBL1223601 Bioactive N-[4-[(1R,5S)-3-azabicyclo[3.1.0]hexan-1-yl]phenyl]-4-butylbenzenesulfonamide
CFAMM00329006 CHEMBL1224638 Bioactive N-[4-[(1R,5S)-3-azabicyclo[3.1.0]hexan-1-yl]phenyl]-4-propan-2-ylbenzenesulfonamide
CFAMM00328997 CHEMBL552279 Bioactive 4-[4-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]phenyl]-N-phenylbenzenesulfonamide
CFAMM00329005 CHEMBL1224697 Bioactive N-[4-[(1R,5S)-3-ethyl-3-azabicyclo[3.1.0]hexan-1-yl]phenyl]-4-propan-2-ylbenzenesulfonamide
CFAMM00329003 CHEMBL1224698 Bioactive 4-propan-2-yl-N-[4-[(1R,5S)-3-prop-2-enyl-3-azabicyclo[3.1.0]hexan-1-yl]phenyl]benzenesulfonamide
CFAMM00328992 CHEMBL1223602 Bioactive N-[4-[(1R,5S)-3-azabicyclo[3.1.0]hexan-1-yl]phenyl]-4-(2-methylbutan-2-yl)benzenesulfonamide
CFAMM00329001 CHEMBL1223657 Bioactive AGN-PC-00QEFH

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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