CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM19387
Family Name Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-3-benzylsulfanyl-2-[[(2S)-2-[(4-chlorophenyl)methyl]-3-sulfanylpropanoyl]amino]propanoic acid family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00187749 Functional Category Bioactive with Natural Product
Superfamily Neprilysin and Cathepsin B Binder Superfamily
Class Class 5316

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid B receptor Ligand Baclofen Family 5 12
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Angiotensin-converting enzyme and Neprilysin Inhibitor M100,24... 18 60
Neprilysin Inhibitor Thiorphan Family 41 68
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-154957 Family 2 3
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-cycl... 1 6
Vasopressin V1a receptor ligand (2R)-3-(4-chlorophenyl)-2-[[2-... 6 2
Angiotensin-converting enzyme and Neprilysin inhibitor (5R,7S)... 1 0
Angiotensin-converting enzyme and Leukotriene A-4 hydrolase in... 7 1
Neprilysin inhibitor methyl (2S)-4-methyl-2-[[2-(sulfanylmethy... 3 0
Cathepsin B inhibitor (2S)-N-[(2S)-1-(4-chlorophenyl)-4-(ethyl... 1 3
Angiotensin-converting enzyme inhibitor AGN-PC-041KG7 family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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