CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1941
Family Name Extracellular calcium-sensing receptor ligand SureCN2972008 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00329015 Functional Category Bioactive
Superfamily Extracellular calcium-sensing receptor Binder Superfamily
Class Class 3462

Cousin Family NamesSeedsMembers
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Reverse transcriptase Inhibitor UK-129485 Family 23 221
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Potassium voltage-gated channel subfamily H member 2 Ligand (1... 64 70
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Tyrosine-protein kinase Lck inhibitor 4-N-(2-chloro-6-methylph... 8 45
Vascular endothelial growth factor receptor 2 and Angiopoietin... 2 11
Histamine H4 receptor ligand AGN-PC-07ZG9H family 4 4
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN97387... 4 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 11
Cathepsin S and Cathepsin K inhibitor SureCN1629664 family 10 11
Extracellular calcium-sensing receptor ligand SureCN2503512 fa... 3 17
Extracellular calcium-sensing receptor ligand SureCN2503519 fa... 1 0
Glucocorticoid receptor ligand (2R)-1,1,1-trifluoro-4-(2-metho... 2 5
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 19 2
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Dihydrofolate reductase inhibitor AC1L9XPA family 6 5
Neuropeptide Y receptor type 1 ligand 1-[3-[1-(cyclohexylmethy... 15 9
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 8 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 16 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
Serine/threonine-protein kinase B-raf and RAF proto-oncogene s... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 7 1
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Leukotriene A-4 hydrolase inhibitor AGN-PC-00EW8S family 1 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Rho-associated protein kinase 2 inhibitor SureCN1519463 family 5 1
Extracellular calcium-sensing receptor ligand SureCN2498142 fa... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00329018 CHEMBL1223771 Bioactive SureCN2976846
CFAMM00329017 CHEMBL1223712 Bioactive SureCN2980689
CFAMM00329015 CHEMBL1223714 Bioactive SureCN2972008
CFAMM00329019 CHEMBL1223772 Bioactive AGN-PC-088XLM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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